Cucumbers and their extracts have been renowned for their anti-inflammatory properties and have a long history of use in traditional medicine. Cultivated in Egypt and India for over 3,000 years, cucumbers were valued for treating sunburns, swelling under the eyes, and various other health challenges.

 

Recent scientific advancements have identified ido-BR1 as the key molecule behind these health benefits. Q-actin utilizes the properties of ido-BR1 to help mitigate inflammation through multiple pathways, preventing joint and tissue damage. These pathways include:

 

• Reducing TNF-α, a protein that triggers inflammation and can lead to the breakdown of cartilage through certain enzymes known as metalloproteinases. Q-actin lowers TNF-α levels, potentially helping to protect cartilage from damage.

 

• Inhibiting key enzymes like α-L-iduronidase and sialidases that are involved in inflammation. These enzymes can degrade glycosaminoglycans (GAGs), which are important for maintaining the structure of connective tissues such as cartilage and tendons. By inhibiting these enzymes, Q-actin helps protect these tissues from inflammation-related damage.

 

• Reducing Hyaluronic Acid (HA). While hyaluronic acid is well-known for its role in lubricating joints, excessive production during periods of inflammation can be counterproductive. High HA levels can bind excessively to receptors like CD44 on immune cells, attracting more inflammatory cells and worsening the condition. Q-actin reduces HA production and prevents excessive binding to CD44, thereby reducing inflammation and swelling.​​​​

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